The clinicopathologic spectrum of rhinophyma
Identifieur interne : 00A437 ( Main/Exploration ); précédent : 00A436; suivant : 00A438The clinicopathologic spectrum of rhinophyma
Auteurs : Filippo Aloi [Italie] ; Carlo Tomasini [Italie] ; Elisabetta Soro [Italie] ; Mario Pippione [Italie]Source :
- Journal of the American Academy of Dermatology [ 0190-9622 ] ; 2000.
Descripteurs français
- KwdFr :
- MESH :
- anatomopathologie : Rhinophyma.
- étiologie : Rhinophyma.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Immunohistochimie, Indice de gravité médicale, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus, Évolution de la maladie.
English descriptors
- KwdEn :
- MESH :
- etiology : Rhinophyma.
- pathology : Rhinophyma.
- Adult, Aged, Aged, 80 and over, Disease Progression, Female, Humans, Immunohistochemistry, Male, Middle Aged, Severity of Illness Index.
Abstract
We report the results of a clinicopathologic study of 17 patients with rhinophyma in different stages of evolution, with particular attention paid to the severe form of this disease. On the basis of clinical features, we identified 2 groups of patients: the first group (12/17 patients) included patients with the common form of rhinophyma, whereas the second one (5/17 patients) included patients with the severe form of the disease. There was no link between the clinical aspect and the duration of the disease. Microscopic examination of specimens obtained from the classic type of rhinophyma substantially showed the histopathologic features of fully developed rosacea, except for the presence of prominent sebaceous hyperplasia. The second group showed a very different histologic pattern displaying marked dermal thickness, absence of folliculosebaceous structures, sclerotic collagen bundles with large amounts of mucin, and spreading telangiectasia. The inflammatory infiltrate was inconspicuous, with numerous interstitial spindle and bizarre cells. Most of the interstitial cells were reactive to factor XIIIa. The severe form of rhinophyma shares many histologic characteristics with elephantiasis caused by chronic lymphedema. (J Am Acad Dermatol 2000;42:468-72.)
Url:
DOI: 10.1016/S0190-9622(00)90220-2
Affiliations:
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On the basis of clinical features, we identified 2 groups of patients: the first group (12/17 patients) included patients with the common form of rhinophyma, whereas the second one (5/17 patients) included patients with the severe form of the disease. There was no link between the clinical aspect and the duration of the disease. Microscopic examination of specimens obtained from the classic type of rhinophyma substantially showed the histopathologic features of fully developed rosacea, except for the presence of prominent sebaceous hyperplasia. The second group showed a very different histologic pattern displaying marked dermal thickness, absence of folliculosebaceous structures, sclerotic collagen bundles with large amounts of mucin, and spreading telangiectasia. The inflammatory infiltrate was inconspicuous, with numerous interstitial spindle and bizarre cells. Most of the interstitial cells were reactive to factor XIIIa. The severe form of rhinophyma shares many histologic characteristics with elephantiasis caused by chronic lymphedema. (J Am Acad Dermatol 2000;42:468-72.)</div></front></TEI><affiliations><list><country><li>Italie</li></country></list><tree><country name="Italie"><noRegion><name sortKey="Aloi, Filippo" sort="Aloi, Filippo" uniqKey="Aloi F" first="Filippo" last="Aloi">Filippo Aloi</name></noRegion><name sortKey="Pippione, Mario" sort="Pippione, Mario" uniqKey="Pippione M" first="Mario" last="Pippione">Mario Pippione</name><name sortKey="Soro, Elisabetta" sort="Soro, Elisabetta" uniqKey="Soro E" first="Elisabetta" last="Soro">Elisabetta Soro</name><name sortKey="Tomasini, Carlo" sort="Tomasini, Carlo" uniqKey="Tomasini C" first="Carlo" last="Tomasini">Carlo Tomasini</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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